Jan Wellford & Cory Delavalle have the FKT for an unsupported thru-hike of the 46 peaks, 7d14h15m starting September 7, 2009. Their route came to 196 miles with about 65,000 feet of elevation gain. The pair carried all their supplies and food, taking only water from natural sources. Delavalle's (very detailed!) report indicates that the 46 peaks had been done as a thru-hike with some resupply drops in 10+d in 2002 by Ed Bunk and Jim Kobak.
7d 14h 15m 0s