The Pennine Way record is held Mike Hartley, who ran the route in 2 days 17 hours 20 minutes and 15 seconds, finishing on the 23rd July 1989.
Mike did 2 years of research on the Way and peaked his training at 170 miles per week. He's still running now in his mid 50s (if not quite as fast or as far). He ran without stopping for sleep. In fact, he stopped only twice for 18 minutes each time, one time for fish chips in Alston! The Way took its toll on his feet - he ran the last 40 miles with a borrowed size 10 shoe on his (ordinarily) size 8 right foot.