I did this as part of the Mohawk/AT loop. My main goal was the full loop but I started with the Mohawk and pushed pretty good to see if I could get both.
The time when I reached the end was 4:14:48, and I subtracted out the AT road section at the start which was 3:43, which yields a final time of 4:11:05.
The trail has pretty challenging terrain to begin with, but the amount of leaves on the ground added to the difficulty. There were also a lot of freshly downed trees to negotiate. On the positive side, the rocks were dry and I used them to hop over the deep-leaf sections. Also, the trail is well-established enough that I could still follow it with the leaf cover. There's some really overgrown thorn sections that slashed up my legs just above the ankles (should have worn longer socks).
I started with 1 liter of water but got thirsty toward the end and quickly grabbed a half-liter from a waterfall on Bonney Brook. Most streams were dry.
I used Sarah (Ports) Conner's gpx which was spot-on, and I also totally agree with her that a better time would be achieved going for one route or the other.