This route follows Europe's second largest river, the Danube, from the Black Sea coast at Sulina in Romania, to the source in Donaueschingen, Germany near the Black Forest.

It passes through eight countries (Romania, Bulgaria, Serbia, Croatia, Hungary, Slovakia, Austria and Germany), four capital cities (Belgrade, Budapest, Vienna and Bratislava). A real mix of terrain, it follows roads, trails, off-road river paths, paved dyke roads, over bridges and border crossings, through tiny remote villages and towns and major cities.