This route begins and ends at the Lupine Meadows Trailhead in Grand Teton National Park. Following the Garnet Canyon Trail, it shares the first 4.5 miles of the approach with the route up the Grand Teton. Once it reaches The Meadows, the route takes a left onto the "trail" through the South Fork of Garnet Canyon. Some loose talus and strenuous boulder hopping leads runners up to the saddle between the Middle Teton and the South Teton, at 11,600ft. At the saddle, runners turn right, then follow the classic Southwest Couloir ascent route up to the Middle Teton summit at 12,804ft.

This is a beautiful route that combines some of the best sections of both the west and east sides of the Teton range with a high point of climbing the Grand Teton before changing sides. The route includes trail, adventurous off trail route finding, and 4th and 5th class climbing. The Teton Crest Uppercut begins at Phillips Pass TH on Teton Pass and follows the classic Teton Crest for roughly 26.5 miles before heading east off trail up Dartmouth Basin.