This route follows the Great River Road, a designated road route that follows the Mississippi River from source to sea. The route begins at the Mississippi headwaters in Lake Itasca, Minnesota and continues 2,000 miles south to Venice, Louisiana where the river meets the Gulf of Mexico.

The route crosses ten states — Minnesota, Wisconsin, Iowa, Illinois, Missouri, Kentucky, Tennessee, Arkansas, Mississippi, and Louisiana. Although the net elevation loss is only 1,475ft, the runner will climb about 50,000ft while following the river's twists and turns, banks, and bluffs.

From Burglauenen (896 m) follow mainly the marked trail of Eiger 35k all the way till the Männlichen upper lift station (2222), where 3 lifts are arriving. Going down over the piste and tarmac road that winds through the ski-area. Down in Grindelwald running back to Burglauenen following the left-side trail of the river Schwarze Lütschine. There are spectacular views during the complete trail! First to the north and west. And later, above the tree line, one can admire the north faces of Jungfrau, Mönch and Eiger.