Sandakphu - Phalut is a very popular trekking route in India (on the boarder with Nepal), which starts from Maneybhanjan & ends at Gorkhey. Another option is to go from Maneybhanjan to Sandakphu and back.  Both routes are about 60km.

A long distance (130km) walking route in the Yorkshire Dales.  May be done in either direction.

In 2019 a race was held on the entire route to commemorate the 50th anniversary.  Results are here: http://punkpanther.co.uk/dales-way-2019-results/

Ben Mitchell proposed this route crossing Yosemite National Park on the east-west axis: